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Kyu Yang Yi Selected Research

(5- (2- methoxy- 5- chloro- 5- phenyl)furan- 2- ylcarbonyl)guanidine

11/2005KR-32570, a novel Na+/H+ exchanger-1 inhibitor, attenuates hypoxia-induced cell death through inhibition of intracellular Ca2+ overload and mitochondrial death pathway in H9c2 cells.
10/2005Effects of KR-32570, a new sodium hydrogen exchanger inhibitor, on myocardial infarction and arrhythmias induced by ischemia and reperfusion.
3/2005Effects of KR-32570, a new Na+/H+ exchanger inhibitor, on functional and metabolic impairments produced by global ischemia and reperfusion in the perfused rat heart.

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Kyu Yang Yi Research Topics

Disease

7Ischemia
04/2013 - 03/2005
5Infarction (Infarctions)
03/2017 - 10/2005
5Hypoxia (Hypoxemia)
03/2006 - 05/2003
4Myocardial Infarction
03/2017 - 10/2005
3Hypertrophy
09/2020 - 11/2016
3Coronary Occlusion
01/2009 - 10/2005
2Heart Failure
09/2020 - 03/2017
2Cardiomegaly (Heart Hypertrophy)
09/2020 - 03/2017
2Myocardial Ischemia (Ischemic Heart Diseases)
05/2017 - 01/2009
2Atherosclerosis
05/2017 - 03/2017
2Pulmonary Hypertension
03/2017 - 11/2016
2Cardiovascular Diseases (Cardiovascular Disease)
03/2017 - 01/2013
2Fibrosis (Cirrhosis)
03/2017 - 11/2016
2Reperfusion Injury
01/2009 - 11/2005
2Acidosis
03/2006 - 03/2005
1Osteoporosis
10/2018
1Heart Injuries
05/2017
1Neointima
05/2017
1Vascular Remodeling
11/2016
1Pulmonary Arterial Hypertension
11/2016
1Inflammation (Inflammations)
11/2016
1Right Ventricular Hypertrophy
11/2016
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
10/2011
1Autoimmune Diseases (Autoimmune Disease)
10/2011
1Anaphylaxis (Anaphylactic Shock)
01/2011
1Leukemia
01/2011
1Cerebral Infarction
01/2009
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2009
1Wounds and Injuries (Trauma)
07/2007
1Edema (Dropsy)
11/2005
1Brain Ischemia (Cerebral Ischemia)
11/2005
1Ventricular Tachycardia
10/2005
1Cardiac Arrhythmias (Arrythmia)
10/2005
1Ventricular Fibrillation
10/2005
1Ventricular Premature Complexes (Premature Ventricular Contraction)
10/2005
1Contracture
03/2005

Drug/Important Bio-Agent (IBA)

6L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
06/2007 - 05/2003
4N- (4- cyano- benzo(b)thiophene- 2- carbonyl)guanidineIBA
01/2009 - 11/2005
3benzothiopheneIBA
03/2017 - 11/2005
3Adenosine Triphosphate (ATP)IBA
03/2006 - 05/2003
3Guanidine (Guanidine Nitrate)FDA Link
03/2006 - 03/2005
3Protein Isoforms (Isoforms)IBA
03/2006 - 12/2004
3(5- (2- methoxy- 5- chloro- 5- phenyl)furan- 2- ylcarbonyl)guanidineIBA
11/2005 - 03/2005
22- (methoxycarbonyl(4- methoxyphenyl)methylsulfanyl)- 1H- benzimidazole- 4- carboxylic acid amideIBA
05/2017 - 01/2009
2KR-36996IBA
05/2017 - 03/2017
2urotensin IIIBA
03/2017 - 11/2016
2Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
04/2013 - 01/2009
2Sodium-Hydrogen ExchangersIBA
07/2007 - 10/2005
2IsoenzymesIBA
06/2007 - 10/2005
2Troponin IIBA
06/2007 - 10/2005
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
06/2007 - 10/2005
2Cytochromes c (Cytochrome c)IBA
03/2006 - 11/2005
2Phosphocreatine (Neoton)IBA
03/2006 - 03/2005
2GlycogenIBA
03/2006 - 03/2005
2KATP ChannelsIBA
12/2004 - 12/2004
2N''- cyano- N- (6- amino- 3,4- dihydro- 3- hydroxy- 2- methyl- 2- dimethoxymethyl- 2H- benzopyran- 4- yl)- N'- benzylguanidineIBA
12/2004 - 12/2004
1G-Protein-Coupled Receptor Kinase 5IBA
09/2020
1Angiotensin IIIBA
09/2020
1Pharmaceutical PreparationsIBA
09/2020
1Class 4 Receptor-Like Protein Tyrosine PhosphatasesIBA
10/2018
14'-(1-(((6,7-dichloro-3- oxo- 2,3- dihydro- 4H- 1,4- benzoxazin- 4- yl)acetyl)(methyl)amino)- 2- (4- morpholinyl)ethyl)- 4- biphenylcarboxylic acidIBA
05/2017
1Therapeutic UsesIBA
03/2017
1Proteins (Proteins, Gene)FDA Link
11/2016
1KR36676IBA
11/2016
1EnzymesIBA
04/2013
1Ribose (D-Ribose)IBA
04/2013
1Diphosphates (Pyrophosphates)IBA
04/2013
1Adenosine (Adenocard)FDA LinkGeneric
04/2013
1DNA (Deoxyribonucleic Acid)IBA
04/2013
1rho-Associated KinasesIBA
01/2013
1KR33426IBA
10/2011
1Immunoglobulin E (IgE)IBA
01/2011
1U63A05IBA
01/2011
1AntigensIBA
01/2011
1Glutamic Acid (Glutamate)FDA Link
01/2009
1zoniporideIBA
01/2009
1Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2009
1AmidesIBA
01/2009
1Carboxylic AcidsIBA
01/2009
1benzimidazoleIBA
01/2009
1MB Form Creatine KinaseIBA
06/2007
1Alanine Transaminase (SGPT)IBA
06/2007
1sabiporideIBA
11/2005
1Cardiotonic Agents (Cardiac Stimulants)IBA
11/2005
1Creatine Kinase (Creatine Phosphokinase)IBA
10/2005
1furanIBA
03/2005
1Lactic Acid (Lactate)FDA LinkGeneric
03/2005
1Oxidants (Oxidizing Agents)IBA
03/2005
1cariporideIBA
03/2005
1Uridine Triphosphate (UTP)IBA
12/2004
1BenzopyransIBA
12/2004
1TransferasesIBA
12/2004
1Protein Kinase C-epsilonIBA
12/2004
1p38 Mitogen-Activated Protein KinasesIBA
12/2004
1BuffersIBA
12/2004
1Protein Kinase CIBA
05/2003
1chelerythrineIBA
05/2003

Therapy/Procedure

3Oral Administration
09/2020 - 11/2016
2Therapeutics
05/2017 - 10/2011
1Ligation
09/2020